• First record of experimentally induced salmon gill poxvirus disease (SGPVD) in Atlantic salmon (Salmo salar L.) 

      Thoen, Even; Tartor, Haitham; Amundsen, Marit; Dale, Ole Bendik; Sveinsson, Karoline Overn; Rønning, Hans Petter; Grønneberg, Estelle; Dahle, Maria; Gjessing, Mona Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-07)
      Salmon gill poxvirus (SGPV) infection is a common denominator in many cases of complex gill disease in the Norwegian salmon farming industry and may, as a single agent infection, result in salmon poxvirus disease (SGPVD). Experiences from the field suggest that stress may be a decisive factor for the induction of SGPVD. Here we investigated the effect of stress hormone treatment on SGPV kinetics and ...
    • Mucosal and systemic immune responses to salmon gill poxvirus infection in Atlantic salmon is modulated upon hydrocortisone injection 

      Amundsen, Marit; Tartor, Haitham; Andersen, Kathrine; Sveinsson, Karoline Overn; Thoen, Even; Gjessing, Mona Cecilie; Dahle, Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-09)
      Salmon Gill Poxvirus Disease (SGPVD) has emerged as a cause of acute mortality in Atlantic salmon (Salmo salar L.) presmolts in Norwegian aquaculture. The clinical phase of the disease is associated with apoptotic cell death in the gill epithelium causing acute respiratory distress, followed by proliferative changes in the regenerating gill in the period after the disease outbreak. In an experimental ...
    • Piscine Orthoreovirus (PRV)-3, but Not PRV-2, Cross-Protects against PRV-1 and Heart and Skeletal Muscle Inflammation in Atlantic Salmon 

      Malik, Muhammad Salman; Teige, Lena Hammerlund; Braaen, Stine; Olsen, Anne Berit; Nordberg, Monica; Amundsen, Marit; Kannimuthu, Dhamotharan; Svenning, Steingrim; Edholm, Eva-Stina Isabella; Takano, Tomokazu; Jørgensen, Jorunn; Wessel, Øystein; Rimstad, Espen; Dahle, Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-06)
      Heart and skeletal muscle inflammation (HSMI), caused by infection with Piscine orthoreovirus-1 (PRV-1), is a common disease in farmed Atlantic salmon (Salmo salar). Both an inactivated whole virus vaccine and a DNA vaccine have previously been tested experimentally against HSMI and demonstrated to give partial but not full protection. To understand the mechanisms involved in protection against HSMI ...